Core Technology

  • SMART™ Platform: The four genetic engineering technologies are embedded in ONE VIRAL PARTICLE

    GCM Therapeutic Virus Engineering Technology

    SMART Platform

    (Synthetic & Multi-Antigen Retargeting Technology)

    Efficiently infecting disease cells, Production of therapeutic virus ONLY in disease cells,
    & Use patient’s immune system to synergize to destroy disease cells

  • 1Self-Targeting by Adapter to bind the key biomarker on the target cell surface

    2Protein engineering of viral envelope protein for binding efficiency to target cel

    3Double targeting by combination of self-targeting adapter(①) and modified gH(②)

    4Selective-Replication of the virus only in target disease cells

    5Strong Immunotherapy effects by delivering chemokine and cytokine genes to the disease region

  • SMART™ Expandability

Available in various indication

A single virus can multi-target tumor tissue

World’s first Triple-targeting on tumors with one virus