Available in various indication
SMART™ Platform: The four genetic engineering technologies are embedded in ONE VIRAL PARTICLE
GCM Therapeutic Virus Engineering Technology
SMART Platform
(Synthetic & Multi-Antigen Retargeting Technology)
Efficiently infecting disease cells, Production of therapeutic virus ONLY in disease cells,
& Use patient’s immune system to synergize to destroy disease cells
1Self-Targeting by Adapter to bind the key biomarker on the target cell surface
2Protein engineering of viral envelope protein for binding efficiency to target cel
3Double targeting by combination of self-targeting adapter(①) and modified gH(②)
4Selective-Replication of the virus only in target disease cells
5Strong Immunotherapy effects by delivering chemokine and cytokine genes to the disease region
SMART™ Expandability
Available in various indication
A single virus can multi-target tumor tissue
World’s first Triple-targeting on tumors with one virus